Clinic Conditions IBS & Gut Health Chronic Fatigue Autoimmunity Skin Conditions ADHD & Neuropsychiatry Thyroid & Hormones Cognitive Health Genova Diagnostics GI Effects® NutrEval® Metabolomics SIBO Breath Test Hormonal Panels Organix® Fatty Acids Adrenal Stress Essential Estrogens Menopause Plus Alzheimer's Assessment Women's Health+ IV Therapy Research 🇸🇪 Swedish version Book Consultation
Investigation · Precision Medicine
Hormones · Gut · Nutrition · Genetics

Women's Health
The root cause. Not the label.

Endometriosis, PCOS, perimenopause, cycle irregularities, unexplained fatigue. These are not isolated hormone problems — they are systemic biological conditions with drivers in the gut, immune system, nutritional status and genetic methylation capacity. MediBalans investigates all of these layers simultaneously.

Order SIBO Breath Test — 3 700 kr

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4Diagnostic layers — simultaneously
250+Foods tested with ALCAT
38Methylation genes — MethylDetox
The Clinical Reality

The hormones are reacting to something upstream.

When conventional hormonal investigation finds 'mildly abnormal' results but no clear diagnosis — or normal results despite significant symptoms — it means the measurement has been done at the wrong level. Hormones are the output of a biological system. The inputs to that system include the gut microbiome, immune reactivity to foods, intracellular nutritional status and genetic methylation capacity.

At MediBalans, hormonal investigation starts by measuring those inputs.

Diagnostic Layer 01

Genova Women's Health+

Urine and saliva hormonal panel measuring oestrogen and its metabolites (2-OH, 4-OH, 16-OH), progesterone, testosterone, cortisol curve, DHEA, melatonin, organic acids and optional SNPs. The data standard blood oestrogen testing cannot provide.

Learn about hormonal panels →
Diagnostic Layer 02

ALCAT — Immune Reactivity

Delayed cellular immune reactivity to 250+ foods, additives and chemicals. Chronic immune activation from reactive foods suppresses progesterone synthesis, disrupts the HPG axis and maintains the systemic inflammation that prevents hormonal balance.

Diagnostic Layer 03

CMA — Cellular Micronutrients

55 intracellular markers measuring nutrients actually inside white blood cells. The cofactors required for hormone synthesis and methylation — magnesium, zinc, B6, B12, folate — may be adequate in serum but deficient at cellular level.

Diagnostic Layer 04

MethylDetox — 38 Genes

COMT Val158Met (oestrogen methylation efficiency), CYP1B1 (oestrogen hydroxylation), MTHFR and 35 additional methylation genes. Defines the genetic ceiling for oestrogen metabolism — essential before hormone therapy in complex cases.

Optional — Gut Layer

GI Effects® Stool Profile

Measures beta-glucuronidase — the gut enzyme that recirculates oestrogen from the colon. Elevated beta-glucuronidase drives oestrogen dominance via enterohepatic recirculation. Essential when gut symptoms co-exist with hormonal complaints.

Learn about GI Effects →
Optional — Stress Layer

Adrenocortex Stress Profile

Four-point cortisol and DHEA across the day. Chronic HPA dysregulation suppresses sex hormone production — cortisol and progesterone compete for the same precursor (pregnenolone steal). Understanding the cortisol pattern is essential in fatigue-dominant presentations.

The Gut-Hormone Connection

Your gut controls your oestrogen.

The gut microbiome regulates circulating oestrogen through beta-glucuronidase — an enzyme produced by certain gut bacteria that deconjugates oestrogen in the colon, allowing it to be reabsorbed rather than excreted.

Elevated beta-glucuronidase (GI Effects)

When beta-glucuronidase is elevated, more oestrogen recirculates rather than being cleared — contributing to oestrogen dominance, heavy periods, PMS and oestrogen-sensitive conditions. This gut-hormone axis is frequently missed when investigation starts with hormone testing alone.

Gut dysbiosis and immune activation

Gut dysbiosis and intestinal permeability drive systemic inflammation that suppresses progesterone synthesis and disrupts the hypothalamic-pituitary-gonadal axis. ALCAT identifies the food-driven immune triggers. GI Effects maps the microbiome disruption. Treating the gut frequently normalises hormonal patterns without direct hormonal intervention.

Conditions We Investigate

Common presentations

Endometriosis — inflammation, oestrogen metabolism, immune reactivity
PCOS — insulin resistance, androgen excess, HPA dysregulation
Perimenopause — progesterone decline, oestrogen fluctuation, sleep disruption
PMS / PMDD — cycle-dependent immune reactivity, serotonin, progesterone
Unexplained fatigue — cortisol rhythm, HPA axis, nutritional status
Thyroid + hormonal combination — immune and methylation drivers
Fertility investigation — nutrient cofactors, methylation, immune burden
Questions

Women's health investigation explained

MediBalans uses Genova Women's Health+ (urine and saliva panel: oestrogen metabolites, cortisol curve, testosterone, DHEA, melatonin, organic acids, optional SNPs), ALCAT immune reactivity testing (250+ foods — immune triggers driving hormonal imbalance), CMA intracellular micronutrient analysis (55 markers — cofactors for hormone synthesis and methylation) and MethylDetox 38-gene panel (COMT, CYP1B1, MTHFR — genetic ceiling for oestrogen metabolism).

The gut microbiome regulates circulating oestrogen through beta-glucuronidase — an enzyme that deconjugates oestrogen in the colon, allowing it to be reabsorbed rather than excreted. Elevated beta-glucuronidase (measured in GI Effects) means more oestrogen recirculates — contributing to oestrogen dominance. Gut dysbiosis also drives systemic inflammation that suppresses progesterone and disrupts the HPG axis.

Yes. Delayed immune reactivity to foods (measured by ALCAT) creates chronic low-grade inflammation that suppresses progesterone synthesis, disrupts the hypothalamic-pituitary-gonadal axis and impairs cortisol regulation. Removing the primary reactive foods is frequently the single most effective intervention in complex hormonal cases — reducing the immune burden the entire endocrine system is operating under.

Yes. Women's Health+ uses urine and saliva collection — home specimens that can be shipped internationally. The initial consultation and results review are conducted via video call in English. Test kits are shipped to your address. Blood-based panels require a local draw at a laboratory near you — we guide you on this.

We can recommend and prescribe bioidentical hormonal therapy where clinically indicated. However, we do not prescribe hormones without first understanding the patient's complete hormonal, gut, nutritional and genetic picture. Prescribing progesterone to a patient whose oestrogen dominance is driven by elevated beta-glucuronidase and food reactivity without addressing those drivers is incomplete treatment.

Related

Explore the full investigation

Genova Test

Genova Hormonal Panels

Women's Health+, Estrogen Metabolism Assessment, Rhythm Plus, Menopause Plus — full overview of hormonal panel options.
Condition

Thyroid & Hormones

Thyroid function is tightly linked to oestrogen and progesterone — investigated together at MediBalans.
Genova Test

GI Effects® — Gut & Hormones

Beta-glucuronidase, microbiome and barrier integrity — the gut layer that drives oestrogen recirculation.

Sample Report

What your results look like

The SIBO breath test provides a clear graphical report with hydrogen and methane measurements every 20 minutes over 3 hours — compared against clinical reference values for diagnosis.

SIBO sample report

Four measurement points

  • 01 Hydrogen — measured every 20 minutes over 3 hours
  • 02 Methane — indicates methanogen bacterial overgrowth
  • 03 Transit Time — oro-cecal transit assessment
  • 04 Response Curve — graphical reading against reference values
Order SIBO Breath Test — 3 700 kr → View full sample report (PDF) →

How does MediBalans SIBO test compare?

A fact-based comparison.

MediBalans / SIBO test GetTested / SIBO test Gutfeeling Labs Holistic SIBO test
MethodLactulose breath testLactulose breath testUrine test (mass spectrometry)Lactulose breath test
Gases measuredH₂ + CH₄ + H₂S (flat line)H₂ + CH₄SIBO metabolites in urineH₂ + CH₄
Collection time3 hours (10 data points)2 hours (7 tubes)Single sample2 hours
Physician interpretation✓ Always included———
Treatment protocol✓—Dietary advice—
LaboratoryGenova, CLIA-cert., USAUnknownLund UniversityISO15189
PriceSEK 3,700SEK 995~SEK 2,200~SEK 995

The difference is not just the price — it is how many gases we measure, how long we measure for, and that a physician interprets the result and writes a treatment protocol.

Book Consultation

Investigate the root cause — not the label.

Book an initial consultation for a clinical assessment of your hormonal situation and a clear picture of which diagnostics are relevant.

Order SIBO Breath Test — 3 700 kr Book Consultation →

Test kit ships to your home. Includes 2 months access to meet mario.

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